6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester 1,1-dioxide

  • Name: 6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester 1,1-dioxide
  • CAS: 70415-50-8
  • Purity: 99%
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Chinese Factory Supply Wholesale 6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester 1,1-dioxide 70415-50-8 with Cheap Price

  • Molecular Formula: C9H8ClNO5S2
  • Molecular Weight: 309.751
  • Vapor Pressure: 0mmHg at 25°C 
  • Melting Point: 198-200oC 
  • Refractive Index: 1.663 
  • Boiling Point: 482.343 °C at 760 mmHg 
  • PKA: 4.50±1.00(Predicted) 
  • Flash Point: 245.513 °C 
  • PSA： 120.53000 
  • Density: 1.728 g/cm3 
  • LogP: 2.45390 

6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic acid methyl ester 1,1-dioxide(Cas 70415-50-8) Usage

InChI:InChI=1/C9H8ClNO5S2/c1-11-6(9(13)16-2)7(12)8-4(18(11,14)15)3-5(10)17-8/h3,12H,1-2H3

70415-50-8 Relevant articles

Method for synthesizing lornoxicam intermediate by one-pot method

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Paragraph 0032-0041, (2018/07/30)

The invention belongs to the technical f...

70415-50-8 Process route

methyl 5‐chloro‐3‐(methylsulfamoyl)thiophene‐2‐carboxylate
70374-37-7

methyl 5‐chloro‐3‐(methylsulfamoyl)thiophene‐2‐carboxylate

bromoacetic acid methyl ester
96-32-2

bromoacetic acid methyl ester

methyl 6-chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylate 1,1-dioxide
70415-50-8

methyl 6-chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylate 1,1-dioxide

Conditions
Conditions Yield
With sodium methylate; In methanol; at 25 - 45 ℃; for 24h; Temperature; Inert atmosphere;
90%
methyl 6-chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylate 1,1-dioxide
70415-50-8

methyl 6-chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylate 1,1-dioxide

Conditions
Conditions Yield
/BRN= 30215/,NaOCH3;

70415-50-8 Upstream products

  • 70374-37-7
    70374-37-7

    methyl 5‐chloro‐3‐(methylsulfamoyl)thiophene‐2‐carboxylate

  • 96-32-2
    96-32-2

    bromoacetic acid methyl ester

70415-50-8 Downstream products

  • 479482-38-7
    479482-38-7

    6-chlorine-4-hydroxy-2-methyl-N-[2-(5'-methyl)thiazolyl]-2H-thieno-[2,3-e]-1,2-thiazine-3-formamide-1,1-dioxide

  • 67-56-1
    67-56-1

    methanol

  • 169759-98-2
    169759-98-2

    6-Chloro-N-{4-[5-(4-fluorophenyl)-2-furanyl]-2-thiazolyl}-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide

  • 169759-57-3
    169759-57-3

    6-Chloro-4-hydroxy-2-methyl-N-(4phenyl-2-thiazolyl)-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide

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