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Details
Manufacturer supply 11-Ketoprogesterone 516-15-4 with sufficient stock and high standard
- Molecular Formula: C21H28O3
- Molecular Weight: 328.452
- Appearance/Colour: white crystalline
- Vapor Pressure: 1.17E-09mmHg at 25°C
- Melting Point: 170-175 °C (lit.)
- Refractive Index: 1.55
- Boiling Point: 487.6 °C at 760 mmHg
- Flash Point: 209.3 °C
- PSA： 51.21000
- Density: 1.14 g/cm3
- LogP: 3.90250
11-Ketoprogesterone(Cas 516-15-4) Usage
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General Description |
11-Ketoprogesterone (also known as 11-Oxoprogesterone, Ketogestin, or DG 322A) is a steroid hormone derivative of progesterone, characterized by the presence of a ketone group at the 11-position of the steroid backbone. It shares structural similarities with progesterone but exhibits distinct biological activity, potentially influencing endocrine pathways. While its exact physiological role remains less defined compared to progesterone, it may interact with steroid hormone receptors or serve as an intermediate in steroid metabolism. Further research is needed to fully elucidate its functional significance. |
InChI:InChI=1/C21H28O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-17,19H,4-9,11H2,1-3H3/t15-,16+,17-,19+,20-,21+/m0/s1
516-15-4 Relevant articles
11-β-hydroxysterols as possible endogenous stimulators of mitochondrial biogenesis as inferred from epicatechin molecular mimicry
Dugar, Sundeep,Villarreal, Francisco,Hollinger, Frank H.,Mahajan, Dinesh,Ramirez-Sanchez, Israel,Moreno-Ulloa, Aldo,Ceballos, Guillermo,Schreiner, George
, (2019/11/28)
Currently, there is great interest in id...
HYDROXYSTEROID COMPOUNDS, THEIR INTERMEDIATES, PROCESS OF PREPARATION, COMPOSITION AND USES THEREOF
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Page/Page column 47; 61; 62, (2016/02/09)
The present invention relates to novel s...
Raw synthesis and mitochondrial function postischemic mitochondria diseases related to the lack or for use in new compd. 11β-hydroxysteroid
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Paragraph 0225, (2016/10/08)
The present invention provides novel com...
New steroid 11-ketone group oxidation synthesizing process
-
Paragraph 0130; 0131; 0132, (2016/10/09)
The invention discloses a new steroid 11...
516-15-4 Process route
-
-
80-75-1,22847-91-2
11-alpha-hydroxyprogesterone
-
-
516-15-4
11-Ketoprogesterone
| Conditions | Yield |
|---|---|
|
With
chromium(VI) oxide;
In
water; acetic acid;
for 1.5h;
|
90%
|
|
With
chromium(VI) oxide; acetic acid;
In
water;
at 20 ℃;
for 1.5h;
|
90%
|
|
With
chromium(VI) oxide; acetic acid;
|
|
|
With
pyridine; chromium(VI) oxide;
|
|
|
With
potassium dichromate; sulfuric acid; chlorobenzene;
|
|
|
With
jones reagent;
|
|
|
With
chromium(VI) oxide; acetic acid;
In
water;
for 1.5h;
|
9 g
|
-
-
53-06-5
Cortisone
-
-
516-15-4
11-Ketoprogesterone
-
-
72-23-1
11-dehydrocorticosterone
| Conditions | Yield |
|---|---|
|
With
trimethylsilyl iodide;
In
chloroform;
for 3h;
Ambient temperature;
|
10%
84% |
|
With
trimethylsilyl iodide;
In
chloroform;
for 2h;
Ambient temperature;
|
10%
84% |
|
With
trimethylsilyl iodide;
In
acetonitrile;
for 3h;
Ambient temperature;
|
27%
46% |
|
With
trimethylsilyl iodide;
In
acetonitrile;
for 3h;
Ambient temperature;
|
27%
46% |
516-15-4 Upstream products
-
565-96-8
11α-hydroxy-5β-pregnane-3,20-dione
-
600-57-7
(8S,9S,10R,11S,13S,14S,17S)-17-Acetyl-11-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
-
80-75-1
11-alpha-hydroxyprogesterone
-
53-06-5
Cortisone
516-15-4 Downstream products
-
565-99-1
UC1017
-
21063-91-2
3,11,20-Trioxo-pregnadien-4,6
-
72-23-1
11-dehydrocorticosterone
-
4368-11-0
1-dehydro-11-oxoprogesterone
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