2-Cyanoacetamide

  • Name: 2-Cyanoacetamide
  • CAS: 107-91-5
  • Purity: 99%
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What is the 2-Cyanoacetamide ?

2-Cyanoacetamide is white to light cream crystalline powder, while it's Molecular Formula is C3H4N2O. 2-Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence and is useful for the automated analysis of carbohydrates as borate complexes. It can also be used in the synthesis of heterocyclic compounds such as pyrazole, pyridine and pyrimidine derivatives. Moreover, it can also be applied for the spectrophotometric assay of the enzyme activity of cellulose in related host cells.

What is the CAS number for 2-Cyanoacetamide ?

The CAS number of 2-Cyanoacetamide is 107-91-5.

More information of 2-Cyanoacetamide 107-91-5 are:

Synonyms

Acetamide,cyano- (7CI);Malonamide nitrile;Propionamide, 3-nitrilo-;Malonic acid, monoamide mononitrile;Kyanacetamid;cyanoiminoaceticacid;Cyanacetamide;amidkyselinykyanoctove;3-Nitrilo-propionamide;2-cyano-acetamid;

CAS?Number

107-91-5

Molecular Formula

C3H4N2O

Molecular Weight

84.0776

Density

1.163 g/cm3

Melting Point

119-121 °C(lit.)

Boiling Point

351.2 °C at 760 mmHg

Flash Point

215 °C

HS CODE

H2CONH2 MOL WT. 84.08

PSA

66.88000

LogP

0.08568

Pka

-1.27±0.10(Predicted)

What is 2-Cyanoacetamide (107-91-5) used for?

2-Cyanoacetamide is an acetic amide with a nitrile functional group, serving as a codon of glutamine that directs the placement of glutamine into a polypeptide. It is a white or light yellow needle crystal or powder, slightly soluble in water, and easily soluble in ethanol. As a starting reagent for vitamin B6 synthesis, it reacts with reducing carbohydrates in borate buffer to produce intense fluorescence, making it useful for the automated analysis of carbohydrates as borate complexes.

InChI:InChI:1S/C3H4N2O/c4-2-1-3(5)6/h1H2,(H2,5,6)

Articles related to 2-Cyanoacetamide:

Article

Source

Cyanoacetamide-based oxime carbonates: An efficient, simple alternative for the introduction of Fmoc with minimal dipeptide formation

Khattab, Sherine N.,Subirós-Funosas, Ramon,El-Faham, Ayman,Albericio, Fernando

, p. 3056 - 3062 (2012)

Synthesis and cytotoxic activity of chalcone analogues containing a thieno[2,3-d]pyrimidin-2-yl group as the A-ring or B-ring

Wang, Fu-Cheng,Peng, Bin,Cao, Sheng-Li,Li, Hong-Yun,Yuan, Xiao-Li,Zhang, Ting-Ting,Shi, Ruifeng,Li, Zhuqing,Liao, Ji,Wang, Hailong,Li, Jing,Xu, Xingzhi

, (2020)

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