1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE

  • Name: 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE
  • CAS: 112108-73-3
  • Purity: 99%
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Details

Quality products?make an important contribution to long-term revenue and profitability. Manufacturer supply top purity 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE 112108-73-3 with GMP standards

1.What is the 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE ?

2-Chloro-4-fluoro-5-nitrotoluene, is used as a pharmaceutical intermediate. It is also used as Ceritinib intermediate.

2-chloro-4-fluorotoluene
452-73-3

2-chloro-4-fluorotoluene

1-chloro-5-fluoro-2-methyl-4-nitrobenzene
112108-73-3

1-chloro-5-fluoro-2-methyl-4-nitrobenzene

Conditions
Conditions Yield
With sulfuric acid; potassium nitrate; at -5 - 20 ℃; Product distribution / selectivity;
81%
With sulfuric acid; potassium nitrate; at -5 - 20 ℃;
81%
With sulfuric acid; potassium nitrate; at -5 - 20 ℃;
81%
With sulfuric acid; nitric acid; at 0 - 5 ℃;
80%
With sulfuric acid; potassium nitrate; at 0 - 20 ℃;
71%
With sulfuric acid; potassium nitrate; at 0 - 20 ℃; for 22h;
51.2%
With sulfuric acid; potassium nitrate; at 0 - 20 ℃; for 0.166667h;
37%
With sulfuric acid; potassium nitrate; Yield given;
With KNO3; In conc. H2 SO4;
2.085 g (80%)
With sulfuric acid; potassium nitrate; In 1,2-dichloro-ethane;
With sulfuric acid; potassium nitrate; In 1,2-dichloro-ethane;
With sulfuric acid; potassium nitrate; at 0 - 20 ℃; for 1h;
With sulfuric acid; potassium nitrate; at -5 - 20 ℃; for 16h;
1.1 g
With sulfuric acid; nitric acid; Cooling with ice;
With sulfuric acid; nitric acid; Cooling with ice;
With sulfuric acid; potassium nitrate; at 20 ℃; for 1h;
3-amino-4-fluorotoluene
452-84-6

3-amino-4-fluorotoluene

1-chloro-5-fluoro-2-methyl-4-nitrobenzene
112108-73-3

1-chloro-5-fluoro-2-methyl-4-nitrobenzene

Conditions
Conditions Yield
With sulfuric acid; potassium nitrate; at -5 ℃; for 1h;
61%

2.What is the CAS number for 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE ?

The CAS number of 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE is 112108-73-3.

More information of 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE 112108-73-3 are:

CAS?Number

112108-73-3

Density

1.418 g/cm3

Melting Point

34-36 °C

Boiling Point

267.555 °C at 760 mmHg

Flash Point

115.614 °C

Vapor Pressure

0.013mmHg at 25°C

Refractive Index

1.549

HS CODE

2904909090

PSA

45.82000

LogP

3.21890

3.What are another words for 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE ?

Synonyms?for?1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE 112108-73-3:Benzene, 1-chloro-5-fluoro-2-methyl-4-nitro-;

4.What is the molecular formula of 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE?

The chemical formula of ?1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE is?C7H5ClFNO2 which containing 7 Carbon atoms,5 Hydrogen atoms,1 Chlorine atoms,1 Fluorine atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE?is 189.574.

5.What is 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE (112108-73-3) used for?

1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE is an organic compound with the molecular formula C7H5ClFNO2. It is a derivative of benzene, featuring a chlorine atom at the 1st position, a fluorine atom at the 5th position, a methyl group at the 2nd position, and a nitro group at the 4th position. 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE is characterized by its potential reactivity and versatility in chemical synthesis, making it a valuable intermediate in various chemical and pharmaceutical applications.

InChI:InChI=1/C7H5ClFNO2/c1-4-2-7(10(11)12)6(9)3-5(4)8/h2-3H,1H3

Relevant articles related to 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE:

Article

Source

Design, synthesis of orally bioavailable novel anaplastic lymphoma kinase (ALK) inhibitor diphenylaminopyrimidine analogs and efficacy study on NCI-H2228 xenografts mice model

Das, Debasis,Wang, Jingbing,Li, Yong,Shi, Jingli,Hong, Jian

, p. 1514 - 1517 (2019)

ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF

-

Paragraph 0106; 0107; 0108, (2017/04/18)

6.Buy 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE with the best price .

Hebei Shengang Trading Co.,Ltd is a quality supplier of 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 1-CHLORO-5-FLUORO-2-METHYL-4-NITRO-BENZENE 112108-73-3.

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